James Walters - University of Cambridge

Jamie Walters did a BSC in Nanotechnology at the University of Leeds. Following this he did a PhD at Cambridge University in Chemical Engineering and Biotechnology, where he developed microcapsules, which acted as optical sensors. Following a post-doc creating point of care biosensors, Jamie is now based at ESPCI in Paris where he co-founded a spin-out company in collaboration with Harvard University, which develops smart release capsules for the production of new oils and fuels.  
Full Name: James Walters
Institution: Cambridge University
Department: Biotechnology and Chemical Engineering
Position: Visiting Research Assistant
Department URL: http://www.ceb.cam.ac.uk/
ULTRASOUND-RESPONSIVE MICROCAPSULES FOR IMAGING AND DRUG DELIVERYUltrasound-Responsive Microcapsules for Imaging and Drug Delivery A scanning electron microscopy image of ultrasound-responsive microcapsules following exposure to high pressure ultrasound waves.Such capsules are promising candidates for future progression in the fields of robotic surgery, sensing and drug delivery. 
A scanning electron microscopy image of an individual sensing capsule used for optical imaging of cellular functions.These capsules demonstrated how a capsule geometry could be used to break the response time limitations of particle based in-vivo sensors.
The application of this new family of sensors will enable new information regarding the influence of drugs, toxins and environmental changes on cell function.
A series of confocal microscopy images through the z-axis of an individual sensing capsule used for optical imaging of cellular functions.
STIMULI-RESPONSIVE PAYLOAD DELIVERY A transmission electron microscopy image of an individual microcapsule releasing it’s payload following the appication of an external trigger. Microcapsules such as these, enable fine control over when and how much of the encapsulated active material is released, thus improving its performance. Microcapsules as a consequence are currently used in number of industries including cosmetics, fragrances, medicines, agrochemicals and foods.
This image shows a fluorescent fibre, imaged using a confocal scanning microscope. This research investigates the use of optical fibres to detect the presence of specific proteins. If a protein binds to the optical fibre, it changes the fluorescence - indicating that the protein is present. Optical fibres have many useful applications, including light-based long-distance communication, and illumination. If you ever wondered how Swarovski crystals appear so dazzling in the shop window, that's thanks to the optical fibres in their display lights which maximise the sparkle!

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