Madeline McNamara - University of Cambridge

Madeline currently pursues a PhD at the Anne McLaren Laboratory for Regenerative Medicine at the University of Cambridge. The images you can see below were submitted when Madeline worked as a researcher at the Department of Stem Cell Biology, University of Cambridge Stem Cell Institute
Madeline is working with common marmoset monkey embryonic stem cells, which are thought to resemble human embryonic stem cells and therefore provide a good model to study the similarities between both species. This could provide an alternative model to using human embryos, which are difficult to use in research due to ethical regulations.
Embryonic stem cells are pluripotent, meaning they can give rise to all the cell types present in the body. The particular cell-line featured on my products is originated from the Common Marmoset Monkey (callithrix jacchus) embryo and has been artificially altered to express a green fluorescent protein. This green fluorescence (coloured dark silver, dark gold & dark bronze on my products) provides a visual cue to determine whether the embryonic stem cells observed under the microscope remain pluripotent.

    
Full Name: Madeline McNamara
   
Institution: University of Cambridge
    
Department: Anne McLaren Laboratory for Regenerative Medicine
     
Position:  PhD Candidate
    
   
STEM CELL COLONY
The image shows a common marmoset monkey embryonic stem cell (embryonic stem cells are the starting point of life) colony. The cell-line is transgenic, which means that it is a mixture of genetic material across different species) and carries a reporter sequence. The image visualises an indicative tool for scientists that helps to identify whether the colonies they are staring down at, from the microscope, are actually pluripotent (pluripotent means that the cell can develop in any other cell) or not.

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