Ngoc Lu-Nguyen - Royal Holloway, University of London

Dr Lu-Nguyen is a young scientist working at Royal Holloway, University of London. She has a strong interest in the use of gene therapy for the treatment of neuromuscular diseases (i.e. Parkinson's, Duchenne Muscular Dystrophy).

Full Name: Ngoc Lu-Nguyen
Institution: Royal Holloway, University of London
Department: School of Biological Sciences
Position: Post-doc research assistant
Context: We have studied gene therapy for Parkinson’s disease and used rats as an experimental animal model. This image shows a transverse section of a rat brain being injected with HIV-1- based lentiviral vectors (on the right hemisphere). Green cells expressed an enhanced green fluorescence protein as a consequence of vector injection. 
Cells from embryonic rat brains were grown in a culture plate. Brain cells attached the plate surface and formed multilayers after several days of culturing. Different markers were used to characterise the cell composition.
This image shows cells from embryonic rat brains growing in a culture plate. Brain cells formed multilayers and generated cell clusters. Different markers were used to characterise the cell composition.
Human embryonic kidney (HEK) cells have been widely used in biology research for many years as these cells are very easy to grow and to transfect readily. In our lab, we use HEK cells particularly as a cell factory to produce therapeutic HIV-1- based lentiviral vectors for several gene therapy applications. This image shows HEK cells expressing an enhanced green fluorescence protein, an indicator usually designed in the vector construct to track the distribution of the vectors.

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