Susan Graham - University of Oxford

Susan is a 3rd Year DPhil student and CDT Oxford Clarendon Scholar at the Department of Engineering Science, University of Oxford

She graduated from the University of Sydney in 2009 with a combined degree in Biomedical Engineering and Medical Science (majoring in immunology and cell physiology). She has now started working on targeted drug delivery using ultrasound for whole organ cancer therapy in the BUBBL group under the supervision of Prof Constantin Coussios and Dr Robert Carlisle. The driver for the current research is to minimise or eliminate the side effects of hemotherapeutics used today. Susan is funded by a Clarendon Scholarship and is part of the Centre for Doctoral Training in Innovation Healthcare.

Susan's research aims to create nanoparticles that can entrap gas on its surface so that bubbles can be carried on a nanoscale before expanding into larger bubbles to collapse as before.  This bubble collapse can then be used in many ways, and in this case she will be using it to release drugs inside a tumour.

      

Full Name: Susan Graham
   
Institution: University of Oxford
    
Department: Department of Engineering Science
     
Position:  3rd Year DPhil student
    
     
CAVICATALYTIC NANOPARTICLES
Nano bubbles usually don't exist by themselves, however they can exist if they are stabilised on a surface. When ultrasound hits these nano bubbles, they can start to oscillate and at high enough pressures they violently collapse sending out shock waves. These shockwaves are detected as energy over a range of frequencies and shown in the image / graph.
Btw.  Peter Tufano, the dean of the Saïd Business School at the University of Oxford currently uses one of UPROSA's MacBook cases designed with the image you can see above!

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